Clinical Studies
Scientific Research & Clinical Studies | KallistaNaturals
At KallistaNaturals, our promise of effective wellness solutions is not just a claim; it’s a commitment backed by rigorous scientific investigation. We are dedicated to formulating products that deliver tangible results, and a key part of this dedication involves leveraging and contributing to clinical research. While the KallistaNaturals 3-Formula System itself is a novel, synergistic approach, the individual ingredients and the scientific principles underpinning our formulations are extensively supported by a wealth of peer-reviewed clinical studies.
Our Approach to Clinical Validation
We build our formulations on a foundation of established scientific evidence. This means:
•Ingredient-Specific Research: We prioritize ingredients that have demonstrated efficacy and safety in human clinical trials. Our team meticulously reviews published research to ensure that the forms and dosages of ingredients we use align with those shown to be effective in scientific settings.
•Mechanism of Action: We focus on ingredients with well-understood mechanisms of action, ensuring that their biological pathways align with the health benefits we aim to provide.
•Synergistic Potential: Our research extends to understanding how different clinically-studied ingredients interact. We aim to create formulations where components work together to enhance overall efficacy, a concept often explored in combination therapy studies.
•Continuous Review: The field of nutritional science is dynamic. We continuously monitor new clinical research and emerging data to refine our understanding and ensure our formulations remain at the forefront of scientific innovation.
Understanding Clinical Studies: What They Mean for You
Clinical studies are systematic investigations conducted in humans to evaluate the effectiveness and safety of a treatment, intervention, or product. They are crucial for establishing scientific credibility and providing evidence-based support for health claims. Key aspects of clinical studies include:
•Randomized Controlled Trials (RCTs): Often considered the gold standard, RCTs involve randomly assigning participants to either a treatment group or a control group (receiving a placebo or standard care). This minimizes bias and allows for stronger conclusions about cause and effect.
•Double-Blind: Neither the participants nor the researchers know who is receiving the treatment, further reducing bias.
•Placebo-Controlled: A control group receives an inactive substance (placebo) to account for the psychological effects of treatment.
•Peer-Reviewed: Studies are reviewed by independent experts in the field before publication, ensuring scientific rigor and validity.
When we refer to clinical studies, we are referencing this body of rigorous, peer-reviewed scientific literature that supports the efficacy and safety of the individual ingredients within our formulas.
Key Areas of Clinical Support for KallistaNaturals Ingredients
Our 3-Formula System is designed to support your body’s needs throughout the 24-hour cycle. The ingredients chosen for RADIATE, AURA, and RESTORE are selected based on their demonstrated efficacy in human clinical trials across various health domains:
RADIATE: Morning Multivitamin (Energy, Focus, Foundational Health)
Clinical research supports the role of key vitamins, minerals, and adaptogens in:
•Energy Metabolism: Studies on B vitamins (e.g., methylated B-complex vitamins) highlight their essential role in converting food into energy and reducing fatigue. Adaptogens like Rhodiola Rosea (RhodioLife®), Panax Ginseng (GS15-4™), and Ashwagandha (Sensoril®) further enhance resilience and sustained energy.
•Cognitive Function: Research on L-Theanine (Suntheanine®) demonstrates its ability to promote calm alertness, while Alpha-Lipoic Acid (Na-R-ALA) supports brain health and function, sharpening focus and enhancing memory.
•Immune Support: Essential vitamins like VitaShine® D3 and PureWay-C® bolster your immune system, while a comprehensive array of chelated minerals (e.g., TRAACS® Zinc Bisglycinate, Magnesium Bisglycinate) ensures optimal absorption for systemic well-being.
AURA: Dual-Action Formula (Metabolism, Skin Radiance, Gut Health)
The ingredients in AURA are chosen for their clinically-backed benefits in:
•**SSkin Health: Advanced Marine Collagen Peptides (2,500 mg, low molecular weight) and Ceramosides™ (30 mg) are clinically shown to boost skin elasticity, firmness, and hydration, reducing the appearance of fine lines and wrinkles..
•Metabolic Support: Green Tea Extract (EGCG) supports fat oxidation and energy expenditure, while Chromium Picolinate aids in healthy blood sugar metabolism. Alpha-Lipoic Acid further supports cellular energy production and glucose utilization.
•Gut Health: A robust Probiotic Blend and Inulin (Chicory Root) work in harmony to cultivate a thriving gut microbiome, supporting efficient nutrient absorption and contributing to overall wellness.
RESTORE: Evening Sleep & Recovery Formula (Restorative Sleep, Cellular Rejuvenation)
RESTORE’s ingredients are selected based on clinical evidence supporting their roles in promoting relaxation and improving sleep quality:
•Rapid Sleep Initiation: L-Tryptophan and 5-HTP (5-Hydroxytryptophan) are precursors to serotonin and melatonin, crucial for regulating sleep cycles. Valerian Root and Passionflower further contribute to calming the mind and preparing the body for rest.
•Sustained Deep Sleep & Cellular Rejuvenation: Magnesium Bisglycinate promotes muscle relaxation and nervous system balance. A powerful antioxidant complex with Astaxanthin and Coenzyme Q10 combats oxidative stress and supports cellular repair processes during deep sleep.
•Morning Freshness & Cognitive Clarity: Lemon Balm and Chamomile contribute to a sense of calm and clarity upon waking, supporting cognitive function and overall well-being throughout the day.
Our Commitment to Transparency and Ongoing Research
We are committed to providing you with clear and accessible information about the science behind our products. While we do not conduct our own clinical trials on the finished KallistaNaturals 3-Formula System at this time, we rely on the robust body of scientific literature supporting our individual ingredients. We encourage you to explore the research yourself and are always available to answer questions about our formulations.
We continuously monitor new scientific discoveries and clinical advancements to ensure our products remain at the forefront of nutritional science. Our formulations are dynamic, evolving as new, compelling evidence emerges, ensuring you always receive the most effective and up-to-date wellness solutions.
References
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[2] Panossian, A., & Wikman, G. (2010). Effects of Adaptogens on the Central Nervous System at the Molecular Level. Pharmaceuticals, 3(1), 188-224. https://www.mdpi.com/1424-8247/3/1/188
[3] Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System—A Focus on Vitamin C, Vitamin D, and Zinc. Nutrients, 12(1), 236. https://www.mdpi.com/2072-6643/12/1/236
[4] Proksch, E., Schunck, M., Zague, V., Segger, D., Degwert, J., & Oesser, S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacology and Physiology, 27(3), 113-119. https://www.karger.com/Article/Abstract/355523
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[7] Sies, H. (1997). Oxidative stress: oxidants and antioxidants. Experimental Physiology, 82(2), 291-295. https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/expphysiol.1997.000291
[8] Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Sciences, 17(12), 1161–1169. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169/
[9] Nobre, A. C., Rao, A., & Owen, G. N. (2008). L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition, 17(S1), 167-168. https://pubmed.ncbi.nlm.nih.gov/18296328/
[10] Sarris, J., & Byrne, G. (2011). A systematic review of insomnia and complementary medicine. Current Psychiatry Reports, 13(6), 490-499. https://link.springer.com/article/10.1007/s11920-011-0238-y
[11] Ferracioli-Oda, E., Qawasmi, A., & Bloch, M. (2013). Meta-analysis: melatonin for the treatment of primary sleep disorders. PloS One, 8(5), e63773. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063773